[et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” background_image=”https:\/\/curi.unipg.it\/wp-content\/uploads\/2025\/09\/laboratorio2.jpg” custom_margin=”||40px||false|false” hover_enabled=”0″ global_colors_info=”{}” alt=”laboratory” title_text=”laboratory” sticky_enabled=”0″][et_pb_row _builder_version=”4.27.4″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” min_height=”260px” sticky_enabled=”0″][et_pb_column type=”4_4″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”0px||0px||false|false” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.27.4″ _module_preset=”default” width=”100%” max_width=”1600px” custom_margin=”||40px||false|false” custom_padding=”|20px||20px|false|false” border_width_all_tablet=”” border_width_all_phone=”1px” border_width_all_last_edited=”on|tablet” border_width_bottom_tablet=”1px” border_width_bottom_phone=”1px” border_width_bottom_last_edited=”on|desktop” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/curi.unipg.it\/wp-content\/uploads\/2025\/09\/Hamilton-MicroLab-STAR_1.png” alt=”Hamilton MicroLab STAR” title_text=”Hamilton MicroLab STAR” align=”center” _builder_version=”4.27.4″ _module_preset=”default” width=”50%” module_alignment=”center” custom_margin=”||||false|false” global_colors_info=”{}”][\/et_pb_image][et_pb_heading title=”Hamilton MicroLab STAR” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h2″ title_font=”|||on|||||” title_font_size=”40px” min_height=”19px” custom_margin=”0px||10px||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|tablet” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”16px” text_line_height=”1.4em” width=”100%” width_tablet=”100%” width_phone=”100%” width_last_edited=”on|desktop” global_colors_info=”{}”]<\/p>\n
Automatic sample preparation system Hamilton MicroLab STAR, capable of autonomously processing up to 192 samples.<\/p>\n
The system can open and close flip-tubes, perform temperature-controlled extractions, shake, centrifuge, purify using SPE plate technology, evaporate, and recover samples.\u2028These features greatly increase laboratory productivity (high-throughput) without compromising analytical performance.<\/p>\n
Furthermore, thanks to a series of automatic checks designed to prevent incorrect volume dispensing, tip blockages, solvent depletion, and dripping, it is possible to work with microvolumes (\u00b5L scale) \u2014 a feature that not only reduces environmental impact but also allows for multiple extractions from very limited sample quantities.<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”|0px||0px|false|false” global_colors_info=”{}”][et_pb_image src=”https:\/\/curi.unipg.it\/wp-content\/uploads\/2025\/09\/Agilent-88907000E.png” alt=”Agilent 8890\/7000E” title_text=”Agilent 8890\/7000E” align=”right” _builder_version=”4.27.4″ _module_preset=”default” width=”50%” module_alignment=”center” global_colors_info=”{}”][\/et_pb_image][et_pb_heading title=”Agilent 8890\/7000E” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h2″ title_font=”|||on|||||” title_text_align=”left” title_font_size=”40px” min_height=”19px” custom_margin=”0px||10px||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|tablet” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”16px” text_line_height=”1.4em” width=”100%” width_tablet=”100%” width_phone=”100%” width_last_edited=”on|tablet” module_alignment=”right” global_colors_info=”{}”]<\/p>\n
Gas chromatograph coupled with a triple quadrupole mass spectrometer Agilent 8890\/7000E, equipped with a dual multi-mode injector, a scan rate of 20,000 u\/sec, MRM scan speed of 800 transitions\/sec, MRM dwell time of 0.5 msec, EI MRM sensitivity <8 fg, and hydrogen as carrier gas.<\/p>\n
The instrument is also equipped with a Gerstel MPS sample manipulator\/injector for liquid analysis, an automated SPME Arrow sample preparation system, and a headspace sampler.<\/p>\n
Its injection flexibility, scanning speed, and sensitivity make this system particularly suitable for the analysis of volatile (or derivatized) compounds through targeted or semi-targeted approaches in any matrix of interest.<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.27.4″ _module_preset=”default” custom_padding=”0px||0px||false|false” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.27.4″ _module_preset=”default” width=”100%” max_width=”1600px” custom_margin=”||40px||false|false” custom_padding=”|20px||20px|false|false” border_width_bottom_tablet=”1px” border_width_bottom_phone=”1px” border_width_bottom_last_edited=”on|tablet” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/curi.unipg.it\/wp-content\/uploads\/2025\/09\/Sciex-QTRAP-6500.png” alt=”Sciex QTRAP 6500+” title_text=”Sciex QTRAP 6500+” _builder_version=”4.27.4″ _module_preset=”default” width=”60%” module_alignment=”center” global_colors_info=”{}”][\/et_pb_image][et_pb_heading title=”Sciex QTRAP 6500+” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h2″ title_font=”|||on|||||” title_font_size=”40px” min_height=”19px” custom_margin=”0px||10px||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|tablet” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”16px” text_line_height=”1.4em” width=”100%” width_tablet=”100%” width_phone=”100%” width_last_edited=”on|tablet” global_colors_info=”{}”]<\/p>\n
Ultra-high-performance liquid chromatograph (UHPLC) coupled with a hybrid quadrupole\u2013collision cell\u2013linear ion trap mass spectrometer Sciex QTRAP 6500+.
\n– MS\/MS scan speed (quadrupole mode): 12,000 scan\/sec
\n– MS\/MS scan speed (trap mode): 20,000 scan\/sec
\n– Polarity switching time in MRM: 5 ms
\n– Acquisition rate in MRM: 500 MRM\/sec
\n– Sensitivity ESI+ <0.28 fg, ESI\u2013 <0.28 fg<\/p>\n
The system\u2019s ability to automatically switch within the same run between triple quadrupole and quadrupole\/ion trap modes provides exceptional selectivity (reducing false positives). Combined with outstanding instrumental performance, this makes it particularly effective for targeted, semi-untargeted, and suspect screening analyses.<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/curi.unipg.it\/wp-content\/uploads\/2025\/09\/Sciex-ZenoTOF-7600.png” alt=”Sciex ZenoTOF 7600+” title_text=”Sciex ZenoTOF 7600+” _builder_version=”4.27.4″ _module_preset=”default” width=”60%” module_alignment=”center” global_colors_info=”{}”][\/et_pb_image][et_pb_heading title=”Sciex ZenoTOF 7600+” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h2″ title_font=”|||on|||||” title_text_align=”left” title_font_size=”40px” min_height=”19px” custom_margin=”0px||10px||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|tablet” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”16px” text_line_height=”1.4em” width=”100%” width_tablet=”100%” width_phone=”100%” width_last_edited=”on|tablet” module_alignment=”right” global_colors_info=”{}”]<\/p>\n
Ultra-high-performance liquid chromatograph (UHPLC) coupled with a hybrid quadrupole\u2013time-of-flight mass spectrometer (UHPLC-QTOF) Sciex ZenoTOF 7600+, equipped with an electron-activated dissociation (EAD) fragmentation system.
\n– MS scan speed: 25 scans\/sec
\n– MS\/MS DDA scan speed: 133 scans\/sec
\n– MS\/MS DIA (SWATH) scan speed: 200 scans\/sec
\n– Mass accuracy \u22641 ppm
\n– Resolution: 40,000 FWHM at 956 m\/z<\/p>\n
The high-resolution time-of-flight technology, combined with the instrument\u2019s scan speed, baseline stability, patented duty-cycle optimization, wide dynamic range, and stable LOD\/LOQ, makes this system ideal for untargeted analyses of highly complex matrices.\u2028Additionally, the EAD system allows discrimination between isomeric compounds that cannot normally be distinguished using traditional fragmentation techniques (CID or HCD).<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.27.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/curi.unipg.it\/wp-content\/uploads\/2025\/09\/Thermo-Orbitrap-Ascend-Tribrid.png” alt=”Thermo Orbitrap Ascend Tribrid” title_text=”Thermo Orbitrap Ascend Tribrid” _builder_version=”4.27.4″ _module_preset=”default” width=”60%” module_alignment=”center” global_colors_info=”{}”][\/et_pb_image][et_pb_heading title=”Thermo Orbitrap\u2122 Ascend Tribrid\u2122” _builder_version=”4.27.4″ _module_preset=”default” title_level=”h2″ title_font=”|||on|||||” title_font_size=”40px” min_height=”19px” custom_margin=”0px||10px||false|false” custom_margin_tablet=”0px||||false|false” custom_margin_phone=”0px||||false|false” custom_margin_last_edited=”on|tablet” global_colors_info=”{}”][\/et_pb_heading][et_pb_text _builder_version=”4.27.4″ _module_preset=”default” text_font_size=”16px” text_line_height=”1.4em” width=”100%” width_tablet=”100%” width_phone=”100%” width_last_edited=”on|tablet” global_colors_info=”{}”]<\/p>\n
Two-dimensional UHPLC system coupled with a hybrid quadrupole\u2013linear ion trap\u2013Orbitrap mass spectrometer (Thermo Scientific\u2122 Orbitrap\u2122 Ascend Tribrid\u2122), equipped with ultraviolet photodissociation (UVPD) fragmentation.
\n– High-resolution MS scan speed: 45 scans\/sec
\n– Low-resolution MS scan speed: 50 scans\/sec
\n– Automatic polarity switching
\n– Resolution: 480,000 FWHM @ 200 m\/z<\/p>\n
The presence of 2D chromatography, high resolution, capability for MS\u00b9\u2070 experiments, inclusion of UVPD fragmentation, and the ability to acquire data simultaneously in high and low resolution (thanks to dual ion routing multipole IRM) make this instrument unique worldwide.\u2028It is essential for analyses where separation and characterization of isomeric or isobaric compounds are critical.\u2028Given its features, this system is particularly suited for proteomics analyses.<\/p>\n
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Automatic sample preparation system Hamilton MicroLab STAR, capable of autonomously processing up to 192 samples. The system can open and close flip-tubes, perform temperature-controlled extractions, shake, centrifuge, purify using SPE plate technology, evaporate, and recover samples.\u2028These features greatly increase laboratory productivity (high-throughput) without compromising analytical performance. Furthermore, thanks to a series of automatic checks designed […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1463","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/pages\/1463","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/comments?post=1463"}],"version-history":[{"count":1,"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/pages\/1463\/revisions"}],"predecessor-version":[{"id":1465,"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/pages\/1463\/revisions\/1465"}],"wp:attachment":[{"href":"https:\/\/curi.unipg.it\/en\/wp-json\/wp\/v2\/media?parent=1463"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}